1. When was the first case of AIDS officially recognized by the U.S. Centers for Disease Control and Prevention (CDC)? a) 1975 b) 1981 c) 1985 d) 1989 Correct Answer: b) 1981

2. Where was the first recognized case of AIDS reported in 1981? a) New York City, USA b) San Francisco, USA c) Los Angeles, USA d) Miami, USA Correct Answer: b) San Francisco, USA

3. What was the original name given to the condition that would later be known as AIDS? a) GRID (Gay-Related Immune Deficiency) b) HTLV-III (Human T-cell Lymphotropic Virus Type III) c) Kaposi's Sarcoma Syndrome d) Immuno-deficiency Syndrome Correct Answer: a) GRID (Gay-Related Immune Deficiency)

4. When was the human immunodeficiency virus (HIV) identified as the cause of AIDS? a) 1981 b) 1983 c) 1985 d) 1987 Correct Answer: b) 1983

5. Who is credited with the discovery of the human immunodeficiency virus (HIV)? a) Robert Gallo b) Luc Montagnier c) Jonas Salk d) Albert Sabin Correct Answer: b) Luc Montagnier

6. When was the term "AIDS" (Acquired Immunodeficiency Syndrome) coined by the CDC? a) 1981 b) 1982 c) 1983 d) 1985 Correct Answer: c) 1983

7. The first antiretroviral drug approved for the treatment of HIV was: a) AZT (zidovudine) b) Nevirapine c) Efavirenz d) Saquinavir Correct Answer: a) AZT (zidovudine)

8. The International AIDS Conference, a significant event in the history of HIV/AIDS, was first held in which year? a) 1985 b) 1987 c) 1990 d) 1995 Correct Answer: b) 1987

9. Who was the first prominent public figure to publicly acknowledge having AIDS, helping to reduce the stigma associated with the disease? a) Freddie Mercury b) Magic Johnson c) Rock Hudson d) Arthur Ashe Correct Answer: c) Rock Hudson

10. The first AIDS cocktail, a combination of multiple antiretroviral drugs, was introduced in which year? a) 1987 b) 1990 c) 1996 d) 2000 Correct Answer: c) 1996

11. The "10th World AIDS Conference" held in Yokohama, Japan, marked a significant milestone. What was unique about this conference? a) It was the first international AIDS conference. b) It unveiled the first effective HIV vaccine. c) It included the first public acknowledgment of AIDS as a global pandemic. d) It revealed the first successful HIV gene therapy. Correct Answer: a) It was the first international AIDS conference.

12. The first community-based AIDS service organization in the United States was: a) Gay Men's Health Crisis (GMHC) b) amfAR (The Foundation for AIDS Research) c) ACT UP (AIDS Coalition to Unleash Power) d) National AIDS Brigade (NAB) Correct Answer: a) Gay Men's Health Crisis (GMHC)

13. When was the first HIV antibody test, allowing for blood screening for HIV, licensed by the U.S. FDA? a) 1981 b) 1984 c) 1985 d) 1987 Correct Answer: c) 1985

14. In what year was the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act enacted in the United States? a) 1988 b) 1990 c) 1992 d) 1995 Correct Answer: b) 1990

15. The first case of pediatric AIDS was reported in a child in which U.S. state? a) New York b) California c) Florida d) Texas Correct Answer: a) New York

16. The HIV/AIDS epidemic in Africa was first recognized in which decade? a) 1960s b) 1970s c) 1980s d) 1990s Correct Answer: a) 1960s

17. The first reported cases of AIDS in Africa were identified in which country? a) South Africa b) Uganda c) Kenya d) Nigeria Correct Answer: b) Uganda

18. The first antiretroviral drug specifically approved for the treatment of HIV infection was: a) AZT (zidovudine) b) Lamivudine (3TC) c) Nevirapine d) Efavirenz Correct Answer: a) AZT (zidovudine)

19. The 13th International AIDS Conference in 2000 was held in which city? a) Durban, South Africa b) Bangkok, Thailand c) Sydney, Australia d) Geneva, Switzerland Correct Answer: a) Durban, South Africa

20. The first World AIDS Day was observed on: a) December 1, 1985 b) December 1, 1988 c) December 1, 1990 d) December 1, 1995 Correct Answer: b) December 1, 1988

21. The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) was established in which year? a) 1998 b) 2000 c) 2003 d) 2005 Correct Answer: c) 2003

22. The 3 by 5 Initiative, launched by the World Health Organization (WHO) and UNAIDS, aimed to provide antiretroviral treatment to how many people by the end of 2005? a) 1 million b) 3 million c) 5 million d) 10 million Correct Answer: b) 3 million

23. The "Berlin Patient," known as the first person to be functionally cured of HIV, underwent a unique medical procedure involving: a) Bone marrow transplant from an HIV-resistant donor b) Stem cell therapy c) Gene therapy targeting HIV d) Retroviral therapy combined with intensive chemotherapy Correct Answer: a) Bone marrow transplant from an HIV-resistant donor

24. The "Swiss Statement" in 2008 suggested that HIV-positive individuals on effective antiretroviral therapy could safely do what in terms of HIV transmission? a) Donate blood b) Have unprotected sex without risk of transmitting the virus c) Share needles without risk of transmitting the virus d) Breastfeed their infants without risk of transmitting the virus Correct Answer: b) Have unprotected sex without risk of transmitting the virus

25. The Joint United Nations Programme on HIV/AIDS (UNAIDS) was established in which year? a) 1985 b) 1992 c) 1996 d) 2001 Correct Answer: d) 2001